Four types of tumor progression after microwave ablation of single hepatocellular carcinoma of ≤5 cm: incidence, risk factors and clinical significance
نویسندگان
چکیده
Objectives To evaluate the incidence, risk factors and clinical significance of four types tumor progression (TP) after microwave ablation (MWA) single hepatocellular carcinoma (HCC) <5 cm.Methods The data 340 treatment-naïve, HCC patients with a cm underwent MWA between April 2012 November 2017 were retrospectively reviewed. TPs including local (LTP), intrahepatic distant recurrence (IDR), aggressive intrasegmental (AIR) extrahepatic (EDR) reviewed compared BCLC stage 0 A. Univariate multivariate analysis performed on clinicopathological variables different to identify affecting long-term overall survival (OS).Results In median follow-up period 25.6 months (range, 3.1–61.4 months), rate LTP, IDR, AIR EDR was 6.2% (21/340), 29.1% (98/340), 3.2% (11/340) 7.9% (27/340). TP occurrence rates in comparable those A (p = 0.492, 0.971, 0.681 0.219). showed that age < 0.001, hazard ratio [HR] 2.783), comorbidities 0.042, HR 1.864), 0.027, 1.719; p 3.628; 0.009, 2.638) independently associated OS. Multivariate older 2.478), 2.648) 0.002, 2.222), poor OS.Conclusions IDR is highest all following <5cm. Old age, had an adverse effect
منابع مشابه
Local Tumor Progression of Hepatocellular Carcinoma After Microwave Percutaneous Ablation: A Preliminary Report
BACKGROUND Microwaves (MW) technology is an ablative treatment alternative to radiofrequency (RF) for early stages of hepatocellular carcinoma (HCC) in cirrhotic patients not suitable for surgical resection. It is well known that HCC lesions ≥ 30 mm treated by RF show a high rate of local tumor progression because of residual of unablated neoplastic tissue. METHODS Aim of this study was to de...
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ژورنال
عنوان ژورنال: International Journal of Hyperthermia
سال: 2021
ISSN: ['1464-5157', '0265-6736']
DOI: https://doi.org/10.1080/02656736.2021.1962548